INTRODUCTION
Helicobacter pylori is gram-negative spiral-shaped bacterium that resides in the human stomach. This bacterium is a common pathogen that damages the gastric mucosa, leading to gastric and duodenal ulcers, as well as stomach cancer – one of the serious gastrointestinal diseases. Therefore, early diagnostic testing is extremely crucial for better disease management.
TopSENSI ® Urease Test Kit is designed to detect H. pylori in the stomach from endoscopic biopsy samples. The kit relies on the fact that H. pylori secretes a significant amount of urease enzyme during its activity, leading to the breakdown of urea into ammonia, which makes the environment alkaline. This change in pH causes the urea-indole solution to change color from yellow to purple.
Highlights
- Simple procedure
- Rapid results turnaround time
Specification
| Target | Screening H. pylori |
| Sample type | Stomach biopsy sample |
| Storage | 2 – 8oC, 06 months from manufacture |
| Detection time | 30 minutes |
| Components of | Urease tube |
Figure 1. Reagent sample after performing the reaction.
Note:
1: Reagent sample when the reaction is negative
2: Sample should be reviewed after 30 minutes.
3, 4: Reagent sample when the reaction is positive
